研究成果

A01班

論文

  • Precession measurement of perturbed angular correlation in double-photon emission nuclides with magnetic field for novel RI imaging method
    Taisei Ueki, Mizuki Uenomachi, Kenji Shimazoe, Hideki Tomita, Kei Kamada, Hiroyuki Takahashi
    Detectors and Associated Equipment 1050, 168122 (2023)
    https://doi.org/10.1016/j.nima.2023.168122
  • Time and Energy Resolving Time-over-Threshold ASIC for MPPC module in TOF-PET system (ToT-ASIC2)
    Orita, T., Uenomachi, M., Shimazoe, K., & Ikeda, H
     Journal of Instrumentation 18(09), P09033 (2023)
    https://doi.org/10.1038/s42005-022-00801-w
  • Background reduction in PET by double Compton scattering of quantum entangled annihilation photons
    Kim, D., Rachman, A. N., Taisei, U., Uenomachi, M., Shimazoe, K., & Takahashi, H
    Journal of Instrumentation 18(07), P07007 (2023)
    https://doi.org/10.1088/1748-0221/18/07/P07007
  • Improvement of double photon emission Compton imaging using angular and polarization correlations in cascade photons
    Kim, D., Ueki, T., Rahman, A. N., Yan, L., Uenomachi, M., Shimazoe, K., & Takahashi, H
    Journal of Instrumentation 18(05), C05012 (2023)
    https://doi.org/10.1088/1748-0221/18/05/C05012
  • Simultaneous multi-nuclide imaging via reconstruction-free double-photon emission coincidence imaging method with parallel hole collimator and slat collimator
    L. Yan, M. Uenomachi, T. Ueki, D. Kim, K. Shimazoe, H. Takahashi, K. Kamada, Y. Shigekawa, A. Nambu, X. Yin, Y. Wang, and H. Haba
    Nuclear Instruments and Methods in Physics Research Section A: Accelerator, Spectrometers, Detectors and Associated Equipment 1053, 168305 (2023)
    https://doi.org/10.1016/j.nima.2023.168305
  • A double photon coincidence detection method for medical gamma-ray imaging
    Mizuki Uenomachi, Kenji Shimazoe, and Hiroyuki Takahashi
    Bio-Algorithms and Med-Systems  18.1, 120-126 (2022)
    https://doi.org/10.2478/bioal-2022-0080
  • Multi-molecule imaging and inter-molecular imaging in nuclear medicine
    Shimazoe, Kenji, and Mizuki Uenomachi
    Bio-Algorithms and Med-Systems  18.1, 127-134 (2022)
    https://doi.org/10.2478/bioal-2022-0081
  • Development of Compton-PET hybrid imaging system with CeBr3-SiPM arrays
    M. Uenomachi, K. Shimazoe, H. Takahashi
    Journal of Instrumentation 17(10), C10002 (2022)
    https://doi.org/10.1088/1748-0221/17/10/C10002
  • Double photon coincidence crosstalk reduction method for multi-nuclide Compton imaging
    M. Uenomachi, K. Shimazoe, and H. Takahashi
    Journal of Instrumentation 17(04), P04001 (2022)
    https://doi.org/10.1088/1748-0221/17/04/P04001
  • Imaging and sensing of pH and chemical state with nuclear-spin-correlated cascade gamma rays via radioactive tracer
    Kenji Shimazoe, Mizuki Uenomachi, and Hiroyuki Takahashi
    Communications Physics 5, 24 (2022)
    https://doi.org/10.1038/s42005-022-00801-w

招待講演

  • 第3回SITワークショップ(Scholars In Training) 招待講演「放射線を視る。放射線で診る。」島添健次 2023年9月24日
  • 日本核医学会PET核医学分科会 PETサマーセミナー2023 招待講演 「PET検出器におけるデータ取得及び信号処理」 島添健次 2023年8月25日
  • 量子生命科学会第5回大会光量子センシングセッション 招待講演「光子対を用いた核医学量子イメージングの展開」 島添健次 2023年5月18日
  • 第70回 応用物理学会 春季学術講演会 放射線分科会内招待講演 「量子もつれ光子対による原子核ー多分子間相互作用プローブを活用した診断治療学の創生」 島添健次 2023年3月17日
  • 日本放射化学会第66回討論会(2022) 原子核プローブ招待講演 「光子時空間相関を用いたイメージング・計測手法の開拓」 島添健次 2022年9月15日
  • アイソトープ・放射線研究会・日本アイソトープ協会奨励賞招待講演 「核医学計測のための多光子相関計測手法の開発」 島添健次 2022年7月8日
  • 4th Jagiellonian Symposium on Advances in Particle Physics and Medicine, “Multi-isotope imaging and quantum chemical sensing with PET and SPECT nuclides” Kenji Shimazoe, July 2022

B01班

論文

招待講演

C01班

論文

  • Aberrant Cadherin11 expression predicts distant metastasis of gastric cancer
    Mita H, Katoh H, Komura D, Kakiuchi M, Abe H, Rokutan H, Yagi K, Nomura S, Ushiku T, Seto Y, Ishikawa S
    Pathol Res Pract 242, 154294 (2023)
    https://doi.org/10.1016/j.prp.2022.154294
  • Multiancestry genomic and transcriptomic analysis of gastric cancer
    Totoki Y, Saito-Adachi M, Shiraishi Y, Komura D, Nakamura H, Suzuki A, Tatsuno K, Rokutan H, Hama N, Yamamoto S, Ono H, Arai Y, Hosoda F, Katoh H, Chiba K, Iida N, Nagae G, Ueda H, Shihang C, Sekine S, Abe H, Nomura S, Matsuura T, Sakai E, Ohshima T, Rino Y, Yeoh KG, So J, Sanghvi K, Soong R, Fukagawa A, Yachida S, Kato M, Seto Y, Ushiku T, Nakajima A, Katai H, Tan P, Ishikawa S, Aburatani H, Shibata T.
    Nat Genet. 55(4), 581-594 (2023)
    https://doi.org/10.1038/s41588-023-01333-x
  • Multivalent Tyrosine Kinase Inhibition Promotes T Cell Recruitment to Immune-Desert Gastric Cancers by Restricting Epithelial-Mesenchymal Transition via Tumor-intrinsic IFN-γ Signaling
    Longlong Cao, Heng Lu, Mohammed Soutto, Nadeem Bhat, Zheng Chen, Dunfa Peng, Ahmed Gomaa, Jiabin Wang, Jianwei Xie, Ping Li, Chaohui Zheng, Sachiyo Nomura, Jashodeep Datta, Nipun Merchant, Alejandro Villarino, Alexander Zaika, Changming Huang, Wael El-Rifai
    Gut., gutjnl-2022-329134 (2023)
    https://doi.org/10.1136/gutjnl-2022-329134
  • Molecular and Immune Profiling of Syngeneic Mouse Models Predict Response to Immune Checkpoint Inhibitors in Gastric Cancer
    Lee D, Choi J, Oh HJ, Ham IH, Lee SH, Nomura S, Han SU, Hur H.
    Cancer Res Treat. 55(1), 167-178 (2023)
    https://doi.org/10.4143/crt.2022.094
  • YWHAG deficiency disrupts the EMT-associated network to induce oxidative cell death and prevent metastasis
    Jeannie Xue Ting LEE1 Wei Ren TAN, Zun Siong LOW, Jia Qi LEE, Damien CHUA, Wisely Duan Chi YEO, Benedict SEE, Marcus Ivan Gerard VOS, Tomohiko YASUDA, Sachiyo NOMURA, Hong Sheng CHENG, Nguan Soon TAN
    Advanced Science, 202301714 (2023)
    https://doi.org/10.1002/advs.202301714
  • Identification of neoantigens in two murine gastric cancer cell lines leading to the neoantigen-based immunotherapy
    Koji Nagaoka, Changbo Sun, Yukari Kobayashi, Takayuki Kanaseki,  Serina Tokita, Toshihiro Komatsu, Kazuhiro Maejima, Junichiro Futami, Sachiyo Nomura, Keiko Udaka, Hidewaki Nakagawa, Toshihiko Torigoe, Kazuhiro Kakimi
    Cancers 14(1), 106 (2022)
    https://doi.org/10.3390/cancers14010106
  • Crosstalk between cancer-associated fibroblasts and immune cells in peritoneal metastasis; inhibition in the migration of M2 macrophages and mast cells by Tranilast
    Yusuke Nakamura Jun Kinoshita · Takahisa Yamaguchi · Tatsuya Aoki· Hiroto Saito · Toshihide Hamabe‐Horiike · Shinichi Harada · Sachiyo Nomura · Noriyuki Inaki · Sachio Fushida
    Gastric Cancer 25, 515 (2022)
    https://doi.org/10.1007/s10120-021-01275-5
  • Loss of YTHDF1 in gastric tumors restores sensitivity to anti-tumor immunity by recruiting mature dendritic cells Journal for ImmunoTherapy of Cancer
    Xiaowu Bai, Chi Chung Wong, Yasi Pan, Huarong Chen, Weixin Liu, Jianning Zhai, Wei Kang, Yu Shi, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Philip Chiu, Jun Yu, Enders Kwok-wai Ng
    Journal for ImmunoTherapy of Cancer 10, e003663 (2022)
    http://dx.doi.org/10.1136/jitc-2021-003663
  • Mouse Gastric Epithelial Cells Resist CagA Delivery by the Helicobacter pylori Type IV Secretion System
    Rejina Shrestha, Naoko Murata-Kamiya, Satoshi Imai, Masami Yamamoto,  Tetsuya Tsukamoto, Sachiyo Nomura, Masanori Hatakeyama
    J. Mol. Sci. 23, 2492 (2022)
    https://doi.org/10.3390/ijms23052492
  • Nucleic acid-triggered tumoral immunity propagates pH-selective therapeutic antibodies through tumor-driven epitope spreading
    Genta Furuya, Hiroto Katoh, Shinichiro Atsumi, Itaru Hashimoto, Daisuke Komura, Ryo Hatanaka, Shogo Senga, Shuto Hayashi, Shoji Akita, Hirofumi Matsumura, Akihiro Miura, Hideaki Mita, Makoto Nakakido, Satoru Nagatoishi, Akira Sugiyama, Ryohei Suzuki, Hiroki Konishi, Asami Yamamoto, Hiroyuki Abe, Nobuyoshi Hiraoka, Kazunori Aoki, Yasumasa Kato, Yasuyuki Seto, Chihoko Yoshimura, Kazutaka Miyadera, Kouhei Tsumoto, Tetsuo Ushiku, Shumpei Ishikawa
    Cancer Sci 114, 321-338 (2023)
    https://doi.org/10.1111/cas.15596
  • Antibody and T-Cell Responses against SARS-CoV-2 after Booster Vaccination in Patients on Dialysis: A Prospective Observational Study
    Moe Kawashima, Hiroaki Saito, Takamitsu Nishiuchi, Hiroki Yoshimura, Masatoshi Wakui, Yuta Tani, Yoshitaka Nishikawa, Fumiya Omata, Morihito Takita, Tianchen Zhao, Chika Yamamoto, Yurie Kobashi, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Toyoaki Sawano, Kenji Shibuya, Junichiro Kazama, Ryuzaburo Shineha, and Masaharu Tsubokura
    Vaccines 11, 260 (2023)
    https://doi.org/10.3390/vaccines11020260
  • The serological diversity of serum IgG/IgA/IgM against SARS-CoV-2 nucleoprotein, spike, and receptor-binding domain and neutralizing antibodies in patients with COVID-19 in Japan
    Yudai Kaneko, Akira Sugiyama, Toshiya Tanaka, Kazushige Fukui, Akashi Taguchi, Kenji Tatsuno, Aya Nakayama, Kazumasa Koga, Yoshiro Kishi, Wang Daming, Chungen Qian, Fuzhen Xia, Fan He, Liang Zheng, Yi Yu, Youichiro Wada, Yoshiaki Wada, Tatsuhiko Kodama, Takeshi Kawamura
    Health Sci Rep 5, e572 (2022)
    https://doi.org/10.1002/hsr2.572
  • Pathological complete remission of relapsed tumor by photo-activating antibody-mimetic drug conjugate treatment
    Yudai Kaneko, Kenzo Yamatsugu, Takefumi Yamashita, Kazuki Takahashi, Toshiya Tanaka, Sho Aki, Toshifumi Tatsumi, Takeshi Kawamura, Mai Miura, Masazumi Ishii, Kei Ohkubo, Tsuyoshi Osawa, Tatsuhiko Kodama, Shumpei Ishikawa, Masanobu Tsukagoshi, Michael Chansler, Akira Sugiyama, Motomu Kanai, Hiroto Katoh
    Cancer Sci 113, 4350-4362 (2022).
    https://doi.org/10.1111/cas.15565
  • Humoral immunity after second dose of BNT162b2 vaccine in Japanese communities: an observational cross-sectional study, Fukushima Vaccination Community Survey
    Yurie Kobashi, Takeshi Kawamura, Yuzo Shimazu, Tianchen Zhao, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Yoshitaka Nishikawa, Fumiya Omata, Morihito Takita, Chika Yamamoto, Makoto Yoshida, Makoto Kosaka, Anju Murayama, Sota Sugiura, Manato Tanaka, Moe Kawashima, Yuna Uchi, Joji Shindo, Tomoyoshi Oikawa, Kenji Shibuya, Tatsuhiko Kodama, and Masaharu Tsubokura
    Sci Rep 12, 18929 (2022)
    https://doi.org/10.1038/s41598-022-21797-x
  • Production and Chemical Separation of 229Pa toward Observation of γ Rays of 229mTh
    Y. Shigekawa, X. Yin, A. Nambu, Y. Wang, and H. Haba
    J. Radioanal. Nucl. Chem. (2023)
    https://doi.org/10.1007/s10967-023-09069-y
  • Tumor Targeting of 211At-Labeled Antibody under Sodium Ascorbate Protection against Radiolysis
    H. Takashima, K. Ohnuki, S. Manabe, Y. Koga, R. Tsumura, T. Anzai, Y. Wang, X. Yin, N. Sato, Y. Shigekawa, A. Nambu, S. Usuda, H. Haba, H. Fujii, M. Yasunaga
    Mol. Pharmaceutics 20, 1156 (2023)
    https://doi.org/10.1021/acs.molpharmaceut.2c00869

招待講演

D01班

論文

招待講演